Pattern of Retinopathy: Although the locus of toxic damage is parafoveal in many eyes, Asian patients often show an extramacular pattern of damage. Dose: We recommend a maximum daily HCQ use of 5.0 mg/kg real weight, which correlates better with risk than ideal weight. Retinal damage caused by hydroxychloroquine Plaquenil muscle pain Itching plaquenil How does chloroquine kill the malaria parasite Current testing for Plaquenil toxicity may include Visual field testing to evaluate for missing spots near the center of the vision. Color photographs of the macula. Fluorescein angiography FA. Optical coherence tomography OCT. Fundus autofluorescence. Multifocal electroretinograms mf. Dec 15, 2004 Multifocal ERG testing can detect abnormal function in chloroquine retinopathy even when the full-field ERG appears normal and visible macular alterations are subtle. The mfERG of patients with retinopathy can be altered in many ways including generalized depression of the mfERG, loss of the central peak waveform, as well as a pericentral loss. With Plaquenil Plaquenil is manufactured in only a 200 mg tablet The typical dosage is either 200 or 400 mg per day 200 mg daily puts anyone under 68 pounds at risk1 400 mg of Plaquenil daily puts anyone under 135 pounds at a higher risk for toxicity Therefore, 200mg of Plaquenil daily is going to be a safe dosage for virtually all adults13 Risk of Toxicity: The risk of toxicity is dependent on daily dose and duration of use. There are no similar demographic data for CQ, but dose comparisons in older literature suggest using 2.3 mg/kg real weight. Erg test plaquenil Electroretinogram - EyeWiki, Multifocal ERG in Practice How expensive is plaquenil per pillEffects of long term use of plaquenilPlaquenil utiPlaquenil and juvenile arthritis blue eyes The AAO guidelines go on to recommend the use of the multifocal electroretinogram multifocal ERG or mfERG as a functional test that can provide objective corroboration for visual fields by documenting parafoveal or extramacular electroretinogram depression in early retinopathy. 1 It is worth noting that the American Academy of Rheumatology AAR also recommends multifocal ERG be used as an objective test during the retinal exam. 6 Multifocal ERG vision testing is a type of light induced. This is Why You Need Multifocal ERG if You Have Plaquenil Patients. Early Plaquenil Toxicity Detected without Bull’s Eye Maculopathy. Using multifocal ERG ring ratios to detect and follow.. Multifocal Electroretinogram mf-ERG This test allows the detection of localized parafoveal or extramacular depression in early retinopathy 10, 15. This has similar sensitivity to visual fields and can provide objective confirmation of suspected paracentral field loss. Roquine Plaquenil; Sanofi, and generic formulations. The effects of toxic medications can be detected and quantified using ERG. Which type of ERG to apply depends on the mechanism and site of retinal toxic-ity. Identifying retinal toxicity due to chloroquine or hydroxychloroquine is a pertinent application of mfERG. SIGNS OF TOXICITY ERG for Diagnosis of Birdshot Chorioretinopathy. Tzekov and Madow 2015 stated that birdshot chorioretinopathy BSCR is a rare form of autoimmune posterior uveitis that can affect the visual function and, if left untreated, can lead to sight-threatening complications and loss of central vision.