Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Plaquenil dose for discoid lupus Plaquenil and allergy medications Some patients decide to stop taking statins, a cholesterol-lowering drug, if they experience side effects. A new study tracked how they did. Nov 12, 2009 Plaquenil is a 6-weeker as far as the benefits are concerned, but it would be more dangerous to stop if you spend a lot of time outside and if this were the summer. If you're gonna experiment, I went off it cold turkey as it didn't hurt to do it that way, but you better get back on before the summer or you could experience a flare-up. With the Plaquenil I don't think you will find much relief in such a short time on it & at half of a workable dose. I have read about people stopping P & flaring up. Those who stopped it abruptly had real problems similar to what you are experiencing. If you really need to get off it, I would taper down slowly, very slowly. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Side effects coming off plaquenil Hydroxychloroquine Side Effects Common, Severe, Long Term., What is the correct way to discontinue use of plaquenil? Itching plaquenilPlaquenil skin side effectsDoxycycline plaquenilPlaquenil toxicity continuing educationCoding for plaquenil vision exam Guys, Are there side effects to stopping Plaquenil? If so, what? How soon after do you feel the effects of Sarcoidosis? Michele. Side effects to Stopping Plaquenil. - Sarcoidosis - Inspire. Hydroxychloroquine plaquenil withdrawl? - LUPUS UK. Plaquenil & Weight Gain/Loss -. Aug 26, 2016 Plaquenil damps down the reactiveness of the receptors that send out your “fighters”, which in us is overactive. Rather than strangling the life out of your immune system like steroid meds do, it attenuates the function to closer to normal. Headaches are a listed side effect of plaquenil, but I haven't heard about it causing muscle and joint pain before. You might want to call his pharmacist and see if those are known side effects of plaquenil, for a more comprehensive answer than I can give. I was on plaquenil for years and had to go off of it after it caused worsening psoriasis. RARE side effects If experienced, these tend to have a Severe expression A Disease With Shrinking And Weaker Muscles Called Myopathy A Disorder Of The Peripheral Nerves That Enable Movement Called.