While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners. "I started the hydroxychloroquine medication a week ago and within the first day or two noticed a big difference in my pain and fatigue with major improvement SLE. Plaquenil and the sun Is plaquenil toxicity reversible Plaquenil avkare Plaquenil painful muscle spasms I can attest to being one of the most sensitive to drugs my docs have ever seen. When I first start a med, I have to split dose into 1/4's and add 1/4 more each week. Yes with plaquenil generic, I have itching, intense I could scratch through my skin. But it does calm down. I also get weird rashes but I get those from the Lupus. Plaquenil hydroxychloroquine "I had only had a mild SLE flare about 30 years ago. I had plenty of the discoid lupus symptoms, but they were easily controlled with avoiding the sun and using sunscreens,especially in the last 20 years. I developed another auto-immune problem about 15 years ago.gluten intolerance or or possible CD. It does not appear to be from the Plaquenil but, simply Lupus. Don't mean to scare you but, this can be caused by Plaquenil OR by Lupus OR M. S. Don't wait to have your eyes checked out if you are having any vision issues or the doctor sees an issue. I have been getting these horrible rashes and they are not related to sun exposure. I am interested to see if anyone here has gotten a rash from Plaquenil after being on it for several months. Plaquenil for lupus rash Lupus Board Index plaquenil rash, Hydroxychloroquine User Reviews for Systemic Lupus. Plaquenil and sun exposure for lupusSle plaquenilPlaquenil cost per pillPlaquenil drug side effects I have actually had this same reoccurring rash for about 5 years, but wasn't diagnosed with lupus until earlier this year. So mine is def not caused by the Plaquenil. My doc cannot find the connection, but the only thing that helps me is Zyrtec I use the generic. I hope this at least helps you find relief with the rash. Plaquenil = Rash? lupus - reddit. Immune & Autoimmune - Lupus How long do your malar rashes.. Plaquenil Hydroxychloroquine Side effects, Images, Uses.. Hi. Been taking plaquenil for 2 weeks. About 10 days ago I came up with a rash on back of my hands. V itchy similar to nettle rashesp at night and in sun. Was unsure whether it was connected to plaquenil or possibly sun as it was a sunny day when it came up. Hydroxychloroquine Plaquenil is a drug that is classified as an anti-malarial drug. Plaquenil is prescribed for the treatment or prevention of malaria. It is also prescribed for the treatment of rheumatoid arthritis, lupus, and the side effects of lupus such as hair loss, joint pain, and more. I wonder if the commencement of the skin rashes and itching is related in some way to this decreased effectiveness of the medication too. So far from the other posts it may seems that Plaquenil may be somehow associated with skin rash that looks like small hives and patchy itchiness.