So far I have no more energy than when I first started and has developed neuropathy which I have just found out from Web MD that this neuropathy is one of the side effects of this med! Saying that by stopping this it would take another 6 months to build up the benefit. There are other meds that can help with what you are experiencing, and if your doctor didn't address that then I would seek out a second opinion... Please don't stop your plaquenil until you are sure it is the right thing to do and in your best interest. Side effects of stopping hydroxychloroquine Excessive sleepiness plaquenil Hydroxychloroquine 200 mg tab mylan May 19, 2004 -- Cutting pills in half is a widely accepted strategy for lowering the cost of prescription medications, and there has even been talk by some insurers of mandating the practice for certain drugs. But a new study involving a commonly prescribed muscle relaxant suggests patients may not be. Ok. so i tried plaquenil to see if it would help my dry eyes and mouth and maybe the progression although i dont have the RA symptoms yet. i tried 200mg 2 tablets-at once. so actually i took 400mg about 3 weeks ago and felt very fluish and my knees hurt very very bad. what dose do most of you start on. should i give plaquenil another try? Sometimes what is suggested no antacid for 4 hours is not necessarily required if it means you can't or don't want to take your plaquenil anymore. The worry is. the antacid will affect the absorption of the plaquenil and the amount your body can absorb. Plaquenil is a 6-weeker as far as the benefits are concerned, but it would be more dangerous to stop if you spend a lot of time outside and if this were the summer. Or maybe another doctor if you're not comfortable w/your current one. Can you break plaquenil in half Plaquenil hydroxychloroquine 200mg is it causing itchy., Tried plaquenil 200mg 2 tablets at once and got very sick. Plaquenil story on cbs tonightPlaquenil leg cramps With the Plaquenil I don't think you will find much relief in such a short time on it & at half of a workable dose. I have read about people stopping P & flaring up. Those who stopped it abruptly had real problems similar to what you are experiencing. If you really need to get off it, I would taper down slowly, very slowly. Hydroxychloroquine plaquenil withdrawl? - LUPUS UK. Plaquenil and heartburn rheumatoid. I'm scared to take plaquenil.. So I did get back on the Plaquenil and got the hair and inflammation lined back out and then I tapered the plaquenil down to 200mg when I was originally on 400. So like Kylie said, give it more time if you can. And yes the symptoms do lessen after your body adjusts. And the B supplements are an excellent idea. I only worry that you being off of plaquenil completely for 2 weeks is going to back fire and start your inflamation again which will take a while for the plaquenil to kick back in. If you start feeling sick with a lupus flare, make sure you call your dr. immediately and see if you can start a low dose of it again. When the physician looked inside, he saw both pink and peach tablets, some split in half. Initially, the patient had been taking a 20-mg tablet twice daily. When the physician lowered the dose to 10 mg twice daily, the new prescription was filled.