She suffered from Sjogren syndrome and inflammatory arthritis and was currently treated with prednisone and methotrexate. She was previously treated with hydroxychloroquine (Plaquenil) 200mg bid (6.5mg/kg) for 10 years, which was stopped one year prior to presentation. Plaquenil reuma Can you drink on plaquenil Purpose To describe the findings in a case of hydroxychloroquine-induced maculopathy using optical coherence tomography OCT Spectralis Heidelberg Engeneering with en-face transversal section. Dence of hydroxychloroquine maculopathy. Table. Clinical, High-Speed Ultra–High-Resolution Optical Coherence Tomography, and Multifocal Electroretinogram Findings From Patients Receiving Hydroxychloroquine Patient No./ Age, y Hydroxychloroquine Dosage, mg/d Diagnosis Treatment, y Symptoms Visual Acuity, OD, OS Color Vision Visual Fields mfERG. Standard Stratus OCT images from patients receiving hydroxychloroquine who have had mild loss of vision. dence of hydroxychloroquine maculopathy. Table. Clinical, High-Speed Ultra–High-Resolution Optical Coherence Tomography, and Multifocal Electroretinogram Findings. ultra–high-resolution optical coherence tomography allows for. Review of systems: Blurred vision, halos, dry eye, dry mouth, gastroesophageal reflux, joint pain Pupils: Reactive to light in each eye from 5 mm in the dark to 2 mm in the light. Extraocular movements: Full, both eyes (OU) Confrontation visual fields: Full OU Intra-ocular pressure The optic nerves appeared healthy with a 0.3 cup-to-disc ratio. Past Ocular History: None Medical History: Sjogren syndrome and inflammatory arthritis, supraventricular tachycardia, anxiety, depression, peptic ulcer disease Medications: prednisone, methotrexate, amitriptyline, ranitidine, estradiol, tizanidine, diltiazem, Restasis Allergies: codeine, droperidol Family History: heart disease, arthritis, cancer Social History: occasional alcohol but no tobacco or intravenous drug use. Plaquenil maculopathy oct images Eye screening for patients taking hydroxychloroquine Plaquenil, CLINICAL SCIENCES High-Speed Ultra–High. - oct- Chloroquine pubchemPlaquenil arthritis foundationCan you get high on hydroxychloroquineDownes sm hydroxychloroquine retinopathy Jan 05, 2020 A complete ophthalmologic examination is recommended before starting or within the first year of starting hydroxychloroquine therapy. During this exam, patients should receive a fundus examination; visual fields and spectral-domain optical coherence tomography SD-OCT should be added if maculopathy is present. Hydroxychloroquine toxicity - EyeWiki. CLINICAL SCIENCES High-Speed Ultra. - oct-. Hydroxychloroquine Plaquenil Toxicity and.. Spectral domain optical coherence tomography SD OCT images, red-free photos, and fundus autofluorescence FAF demonstrate a spectrum of findings seen with different stages of hydroxychloroquine retinopathy. Note the increased signal of choroidal vessels. Toxic maculopathy is a form of retinal toxicity that is associated with antimalarial agents such as plaquenil and chloroquine. Both medications are commonly used to treat patients with systemic autoimmune diseases that include the following The presence of bull’s-eye maculopathy indicates the disease has been progressing for years, resulting in foveal thinning and likely vision loss. 8 SD-OCT is a highly sensitive and reproducible imaging modality used in the detection of Plaquenil retinal toxicity. The preferential loss of photoreceptor IS/OS junction makes SD-OCT an ideal tool.