Additionally, another exception occurred while executing the custom error page for the first exception. This article focuses upon hydroxychloroquine retinopathy. Chloroquine was originally used as an anti-malarial therapeutic. Chloroquine and breast cancer Drug reaction with acyclovir and sucralfate and hydroxychloroquine How long should you take hydroxychloroquine Plaquenil and lyme disease Patients suffering from chloroquine and hydroxychloroquine retinal toxicity were referred for study. All of the studies were carried out between 19, giving a 30-year experience. This is a retrospective study of these patients. The patient population included three cases of chloroquine and 26 cases of hydroxychloroquine retinal toxicity. Hydroxychloroquine has significantly less retinal toxicity and has largely replaced chloroquine as a treatment of inflammatory disease. Unfortunately, the retinal damage from these medications is largely irreversible, so it is critical to detect early retinal toxicity in the hopes of limiting the extent of visual loss. Advanced hydroxychloroquine toxicity presents as a bullseye maculopathy. Since retinal toxicity is usually irreversible, early detection of retinal toxicity and cessation of the offending agent is the best treatment. Corneal toxicity presents as an intraepithelial deposition of the drug into the cornea, which rarely affects vision. In the United States, hydroxychloroquine is most often used for its anti-inflammatory effects in rheumatology and dermatology. Chloroquine is now uncommonly used in favor of its derivative hydroxychloroquine. Plaquenil retinal toxicity treatment Multimodal Imaging in Plaquenil Toxicity, Hydroxychloroquine Plaquenil Toxicity and. Do you need a baseline eye exam before taking hydroxychloroquineChloroquine spCan plaquenil stop workingNeutropenia hydroxychloroquine This article is from June 2011 and may contain outdated material. Download PDF. Many systemic medications may cause retinal toxicity. One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine Plaquenil, a chloroquine derivative. Hydroxychloroquine-Induced Retinal Toxicity - American.. Hydroxychloroquine toxicity - EyeWiki. Retinal toxicity secondary to Plaquenil therapy.. Some side effects of hydroxychloroquine may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Ocular Surgery News The American Academy of Ophthalmology has published several dosing and screening recommendations for hydroxychloroquine to avoid potential retinal toxicity, yet some patients. METHODS A prospective and continuing evaluation was made of the potential retinal toxicity of hydroxychloroquine in a cohort of 360 Greek patients followed for RA and SLE, 58 of whom have received long term treatment six years.