Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. Hydroxychloroquine sulfate tablets 400mg Chloroquine phosphate 500 mg side effects Anti-malarials - Hydroxychloroquine is a mainstay of treatment for mild to moderate lupus. It has an anti-inflammatory effect as well as providing some protection against sunlight and is often used as the first line of treatment. Hydroxychloroquine is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Important information Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye. Learn about the medication hydroxychloroquine for Lupus Treatment at Brigham and Women's Hospital. skip to Cookie Notice Skip to contents. Visitor Advisory Patients are limited to one visitor per day to minimize the potential for virus exposure and to protect both patients and staff. Plaquenil is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. This medicine is not effective against all strains of malaria. How does hydroxychloroquine treat lupus What Exactly Is Hydroxychloroquine, The Drug That Is Being., Hydroxychloroquine Uses, Dosage & Side Effects - Chloroquine 500 mgIs plaquenil a quinolonePlaquenil helps joint painDoes a daily dose if plaquenil help with joint painLong term plaquenil use Hydroxychloroquine Plaquenil is used to treat malaria, lupus, and rheumatoid arthritis. Learn about side effects, warnings, dosage, and more. Hydroxychloroquine Side Effects, Dosage, Uses, and More. Lupus Medicines Hydroxychloroquine - Brigham and Women's.. How is plaquenil hydroxychloroquine used to treat lupus?. Hydroxychloroquine is a one of a number of drugs which have been used for many years in the treatment of malaria. Fortunately, it was discovered these drugs often are helpful in the treatment of various rheumatic diseases, particularly systemic lupus erythematosus SLE or "Lupus" and rheumatoid arthritis. What Conditions Does This Treat? Originally, hydroxychloroquine was used to prevent and treat malaria and was considered very effective. Now it is generally used for rheumatoid arthritis, but it has also been shown to work well for juvenile arthritis, some lupus symptoms, and other types of autoimmune conditions. But, the use of the drug expanded in part due to observations made during World War II. Many people were using quinine or synthetic versions of it to prevent malaria. Doctors noticed that rheumatic symptoms improved when taking quinine, which led to the use of medications like Plaquenil to combat lupus.