Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria. Weight loss with plaquenil Hydroxychloroquine 300 mg Summary Abdominal pain is found among people who take Plaquenil, especially for people who are female, 60+ old, have been taking the drug for 5 - 10 years, also take medication Enbrel, and have Pain. While these medications contain the same active ingredient, the preparation of generic hydroxychloroquine can sometimes cause stomach irritation. This sort of upset usually does not occur with commercial Plaquenil. Your doctor can ensure that you receive this version of the medication by writing “do not substitute” on your script. I started taking Plaquenil 4 weeks ago for non specific autoimmune disease as indicated by ANA. Symptoms were low grade temperature off and on for a year, joint pain and fatigue. I have already felt some relief. Some nauseau at first but less problem with fever and joint pain. But, now I have started having stomach cramps and diarrhea. I understand these may go away. Is there anything I can. Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye. Hydroxychloroquine is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Hydroxychloroquine and stomach pain Stomach cramps from Plaquenil - what to do? Lupus Forums at., Treating Lupus with Anti-Malarial Drugs Johns Hopkins Lupus. What are the most common side effects of plaquenilPlaquenil retinal screening interval Side effects include irritability, headache, weakness, hair lightening or loss, stomach upset, nausea, dizziness, muscle pain, rash and itching. Rarely, hydroxychloroquine can affect the bone marrow leading to reduced white blood cells leukopenia or platelets thrombocytopenia and abnormal red blood cells anemia. Hydroxychloroquine Plaquenil Side Effects & Dosage for Malaria. Stomach problems with Plaquenil • Johns Hopkins Arthritis Center. Plaquenil hydroxychloroquine Basics, Side Effects & Reviews.. Nov 09, 2018 Hydroxychloroquine is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria. Hydroxychloroquine is usually taken with food or milk to prevent stomach upset. The dosage and length of treatment are based on your medical condition and response to therapy. In children, dosage. The exact hydroxychloroquine mechanism of action is unclear, although it does work to interrupt the communication of immune system cells to decrease swelling, pain, and joint damage. 1, 2, 3, 5 From the community “My Rheumatologist recently put me on Hydroxychoroquine for treating osteoarthritis and joint cysts in my hands and every other.