Does plaquenil help with inflammation

Discussion in 'Chloroquine Phosphate' started by macle, 12-Mar-2020.

  1. .Stim. Guest

    Does plaquenil help with inflammation


    While there is good clinical evidence demonstrating the drug’s efficacy in rheumatoid arthritis and lupus, there are very few studies looking at hydroxychloroquine as a treatment for Sjögren’s. The studies that do exist show mixed results (some show Nonetheless, despite the lack of clinical studies, rheumatologists feel that hydroxychloroquine may have a potential beneficial effect in helping patients with symptoms of fatigue and achiness, which are common complaints in patients with Sjögren’s.

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    A therapeutic level in the blood, skin, and joints may take up to 3 months to achieve, therefore, the patient must be treated for at least 3 months and preferably 6 months before a decision regarding effectiveness can be made. The mechanism of action is thought to be anti-inflammatory, but Plaquenil also seems to reduce sensitivity to sunlight. Specifically, anti-malarial medications have shown to improve muscle and joint pain, skin rashes, pericarditis inflammation of the lining of the heart, pleuritis inflammation of the lining of the lung, and other lupus symptoms such as fatigue and fever. Plaquenil reduces inflammation in many Rheumatic disorders, the mode of action is pretty complicated though so I shan't bore you with all the details, but basically it prevents your dendritic cells these are messengers for your immune system, if you will from interacting with your T-Cells a special type of white blood cell which through a convoluted and boring process, causes inflammation.

    The good news is that hydroxychloroquine targets the immune system without causing an increase in the risk of infection or cancer that can be seen with other immunosuppressant medications. How the drug works is unclear, but recent research has pointed to an inhibitory effect on toll-like receptors that are proteins involved with inflammation.

    Does plaquenil help with inflammation

    Plaquenil for fatigue and pain DailyStrength, Treating Lupus with Anti-Malarial Drugs Johns Hopkins.

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  6. Side effects include irritability, headache, weakness, hair lightening or loss, stomach upset, nausea, dizziness, muscle pain, rash and itching. Rarely, hydroxychloroquine can affect the bone marrow leading to reduced white blood cells leukopenia or platelets thrombocytopenia and abnormal red blood cells but potentially serious eye toxicity can occur.

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    How to use Plaquenil Hydroxychloroquine is usually taken with food or milk to prevent stomach upset. The dosage and length of treatment are based on your medical condition and response to therapy. A month ago I started on Plaquenil and prednisolone. It has helped a bit with the inflammation but on reading various items on the Internet, Plaquenil seems to be for joint pain and inflammation but skin is not mentioned. I seem to be able to keep that in check with my daily Pilates and if that is its main effect I would rather not take it. Plaquenil is sometimes prescribed to treat inflammation in people with psoriatic arthritis. Plaquenil is also known by its drug name, Hydroxychloroquine. Plaquenil should be used with caution in people with skin symptoms of psoriasis since it can cause a severe flare-up.

     
  7. re-serg Guest

    Hydroxychloroquine is widely used in the treatment of post-Lyme arthritis. Antibiotics Helpful for Rheumatoid Arthritis The Dr. Oz Show Hydroxychloroquine sulfate and Doxycycline drug interactions. Hydroxychloroquine-Induced Retinal Toxicity - American Academy of.
     
  8. GalaXyMan New Member

    , a parasite of Old World (Eastern Hemisphere) monkeys, has been documented as a cause of human infections and some deaths in Southeast Asia. DailyMed - CHLOROQUINE PHOSPHATE tablet Malaria Prophylaxis. The ABCD of Malaria Prophylaxis. Patient Drug resistance in malaria - World Health Organization
     
  9. Vasyasnow Guest

    Plaquenil Oral Uses, Side Effects, Interactions. Find patient medical information for Plaquenil Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings.

    Hydroxychloroquine information booklet - Versus Arthritis
     
  10. h7h2v Guest

    Retinal toxicity associated with chronic exposure to. Hydroxychloroquine sulfate HCQ, Plaquenil is an analogue of chloroquine CQ, an antimalarial agent, used for the treatment of systemic lupus erythematosus, rheumatoid arthritis and other autoimmune disorders. Its use has been associated with severe retinal toxicity, requiring a discontinuation of therapy.

    Hydroxychloroquine Plaquenil