If a patient is overweight, one should use the ideal body weight to assess whether the doaily dose is in the toxic range (/= 6.5 mg/kg/day). This graph shows various formulas that have been proposed for deriving ideal body weight for women, because virtually all cases of hydroxychloroquine toxicity have been female. Hydroxychloroquine does Plaquenil and tramadol Does plaquenil make you tired Does hydroxychloroquine affect osseointegration By the old standards, obese people, if dosed by their actual weight, could be overmedicated, Dr. Marmor said. If you’re short, the standard prescription of 200 mg of Plaquenil, twice daily, is too much, he said. The recommended dosage is no more than 6.5 mg/kg/day, using the standard known as “ideal weight,” which factors in height. Dr. Irreversible retinal damage observed in some patients who had received hydroxychloroquine sulfate; significant risk factors for retinal damage include daily doses of hydroxychloroquine sulfate greater than 6.5 mg/kg 5 mg/kg base of actual body weight, durations of use greater than five years, subnormal glomerular filtration. Plaquenil hydroxychloroquine belongs to a group of medicines called quinolines. Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. For this dosage, any woman with an ideal body weight less than 135 pounds would be in the toxic dose range. The usual hydroxychloroquine dose that is prescribed is 400 mg/day. Plaquenil dosage by weight Plaquenil Hydroxychloroquine Uses, Dosage, Side Effects., Plaquenil hydroxychloroquine sulfate dosing, indications. Lichen planus plaquenilEfectos de hydroxychloroquineHydroxychloroquine sul 200Plaquenil and discoid lupus dosage The AAO published dosing and screening recommendations for chloroquine and hydroxychloroquine in 2016, revising previous recommendations published in 2011. The current maximum daily HCQ dose recommended by the AAO is 5 mg/kg of real weight. Despite Plaquenil dosing recommendations, retinal toxicity.. Plaquenil Uses, Dosage & Side Effects -. Hydroxychloroquine Plaquenil Dosing Calculator - MDCalc. Plaquenil Dosage Malaria. Adults 400 mg 310 mg base once weekly on the same day of each week starting 2 weeks prior. Lupus Erythematosus. The recommended adult dosage is 200 to 400 mg 155 to 310 mg base daily. Rheumatoid Arthritis. The action of hydroxychloroquine is cumulative and may. Although the incidence of macular toxicity is infrequent with Plaquenil use at a dosage of 200mg or 400mg q.d. its visual impact can be devastating. 2,3 The associated classic retinal toxicity is described as a bull’s eye maculopathy ring of depigmented retinal pigment epithelium that spares the foveal area. Any concerns regarding dosage should be discussed with the prescribing physician. Discussion. A risk factor for Plaquenil hydroxychloroquine retinotoxicity is a daily dose that exceeds 5.0 mg of drug per kg of body weight. The tool on the right simply calculates this threshold based on a ppatient’s real body weight.