Chloroquine chemistry

Discussion in 'Generic Chloroquine' started by smolin11, 17-Mar-2020.

  1. Zikdelk Well-Known Member

    Chloroquine chemistry


    It will look at – in detail – quinine and quinine-related drugs. In a previous article, we briefly described malaria and artemisinin as a lead compound for new antimalarials.

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    Pharmacology of Chloroquine Mechanism of Action As mentioned earlier, chloroquine is effective against the erythrocytic form of the Plasmodium parasite. Chloroquine is able to accumulate at very high concentrations within the acid compartments of the parasite. At present, the absolute mechanism of accumulation of the drug is still under debate. CHEMISTRY Acids & Bases. This protein may act as a transporter of organic cations, and have a role in the transport of chloroquine and quinidine-related compounds in kidney. Two alternatively spliced transcript variants encoding the same protein have been described. provided by RefSeq, Oct 2010 Now that chloroquine is in the news everywhere, I thought it might be interesting to have a closer look at the compound. The first part of this post will be chemistry-heavy, further down we'll get into the pharmacology and medical uses. Chloroquine's fame is as an antimalarial drug, and the h

    Understanding the chemistry of these compounds also, as it happens, makes it much easier to comprehend the pharmacology and therapeutic management of malaria itself. We now turn our attention to the other antimalarial drugs.

    Chloroquine chemistry

    Organic chemistry - Synthesis of chloroquine from 4-amino., Chloroquine Sigma-Aldrich

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  3. What are the chemical processes used to make chloroquine? Chemistry 17/12/2019 PM answersmine. Please Login To View The Answer. LOGIN JOIN. Post your answer. Related Questions in Chemistry. When dissolving occurs,_--- all molecules are not in motion, so they run into each other, and collisions of molecules is what makes a substance.

    • What are the chemical processes used to make chloroquine..
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    Oct 01, 2018 Chloroquine phosphate tablets, Chloroquine phosphate, USP, is a 4-aminoquinoline compound for oral administration. It is a white, odorless, bitter tasting, crystalline substance, freely soluble inwater. Chloroquine phosphate tablets are an antimalarial and amebicidal drug. Chloroquine is a medication used to prevent and to treat malaria in areas where malaria is known to be sensitive to its effects. Certain types of malaria, resistant strains, and complicated cases typically require different or additional medication. Chloroquine is a member of the drug class 4-aminoquinoline. Chloroquine Phosphate is the phosphate salt of chloroquine, a quinoline compound with antimalarial and anti-inflammatory properties. Chloroquine is the most widely used drug against malaria, except for those cases caused by chloroquine resistant Plasmodium falciparum.

     
  4. Quqush Well-Known Member

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  5. Vectorix Well-Known Member

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    Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses
     
  6. Geleon XenForo Moderator

    Chloroquine Side Effects Common, Severe, Long Term - Jul 30, 2019 Applies to chloroquine compounding powder, injectable solution, oral tablet. Ocular. Maculopathy and macular degeneration may be irreversible. Irreversible retinal damage has been reported in patients receiving long-term or high-dose 4-aminoquinoline therapy. Retinopathy has been reported as dose related.

    Chloroquine - Wikipedia