Chloroquine in lactation

Discussion in 'Generic Chloroquine' started by ChPeter, 16-Mar-2020.

  1. Bobobsdo New Member

    Chloroquine in lactation


    Chloroquine has been extensively used in mass drug administrations, which may have contributed to the emergence and spread of resistance. It is recommended to check if chloroquine is still effective in the region prior to using it.

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    Chloroquine is an antimalarial medication which is used in the treatment as well as prophylaxis of malaria. This medicine is not recommended in patients with the eye disease. Liver function and blood cell count monitoring is necessary while receiving this medicine. Know Chloroquine uses, side effects, dosage, contraindications, benefit, interactions, purpose, drug interactions, precautions. Very small amounts of chloroquine are excreted in breast milk; when given once weekly, the amount of drug is not sufficient to harm the infant nor is the quantity sufficient to protect the child from malaria. United Kingdom malaria treatment guidelines recommend that weekly chloroquine 500 mg be given until breastfeeding is completed and primaquine can be given.1 Breastfeeding infants should. Eleven women were given 600 mg of chloroquine base orally. The peak chloroquine plus desethylchloroquine in milk averaging 4.4 mg/L occurred an average of 14.4 hours after the dose. Chloroquine and desethylchloroquine were detected in the urine of the 4 infants who were tested.

    The Centers for Disease Control and Prevention recommend against treatment of malaria with chloroquine alone due to more effective combinations. In areas where resistance is present, other antimalarials, such as mefloquine or atovaquone, may be used instead.

    Chloroquine in lactation

    Chloroquine Oral Route Before Using - Mayo Clinic, Chloroquine - Drugs and Lactation Database LactMed - NCBI.

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  4. Safety in Lactation Antimalarials Published 20th May 2012, updated 19th April 2016. Wherever possible, travelling into endemic countries should be delayed until after the lactation period.

    • Safety in Lactation Antimalarials – SPS - Specialist..
    • Chloroquine - Drugs and Lactation Database LactMed..
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    Chloroquine crosses the placenta and is also found in low levels in breast milk, so pregnancy and lactation are often listed as contraindications to its use see DermNet NZ’s pages on Safety of medicines taken during pregnancy and on Lactation and the skin. However, effects on the fetus and baby have been rarely reported and chloroquine has been continued during pregnancy and lactation when required for malaria. Can I take Chloroquine while breastfeeding? Very small amounts of chloroquine are excreted in breast milk; when given once weekly, the amount of drug is not sufficient to harm the infant nor is the quantity sufficient to protect the child from malaria. If not breastfeeding, either drug can be used. For women who are breastfeeding infants with normal G6PD activity, primaquine phosphate can be given. Tafenoquine is not recommended during breastfeeding. Pregnant women diagnosed with severe malaria should be treated aggressively with parenteral antimalarial therapy as described below.

     
  5. kvt Guest

    Plaquenil is the brand name for the prescription drug hydroxychloroquine. Plaquenil Hydroxychloroquine - Side Effects, Dosage, Interactions - Drugs Hydroxychloroquine Indication, Dosage, Side Effect. Hydroxychloroquine Sulphate Indications, Pharmacology.
     
  6. madgaz XenForo Moderator

    Hydroxychloroquine is a quinoline medicine used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Acetyl salicylic acid asprin, micronutrients and chloroquine in the. Health Pros and Cons of Aspirin Patient Advice US News
     
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