I was diagnosed with discoid lupus 18 years ago and was prescribed Plaquenil, which I have taken since then. In October 2012, I was also diagnosed with Sjogrens Syndrome but, as I was already taking Plaquenil, was advised the treatment was the same for Sjogrens. Plaquenil and psoriasis Hydroxychloroquine and hashimoto's disease Chloroquine adverse effects mnemonics Is hydroxychloroquine good when out of date Anemia or low white blood count Although Sjögren’s syndrome is often treatable, this disease is poorly understood and cannot be cured with current medications. Sjögren’s syndrome is often not diagnosed correctly. In part, this is because dry eyes and dry mouth are common symptoms. The main inclusion criteria were age 18 years, serum hemoglobin level ≥10 g/dL, white blood cell count ≥4000/mL, plasma platelet count in the range of 150.000–400.000/mL, glomerular filtration rate ≥70 cc/mL, serum Aspartat aminoteransferase AST and Alanin Aminoteransferase ALT levels less than 1.5-times of the upper normal limit. This means many people taking Plaquenil for RA are taking a dose of 400mg a day or higher. An abnormally low number of white blood cells can lead to infection, because white blood cells defend the body against bacteria. From research I have done online, I gather that low white cell count can also be a symptom of the Sjogrens in itself. At a recent medical with my doctor, blood tests were taken and I had a call a couple of days later telling me to stop taking g Plaquenil immediately as I have a very low white cell count and that it is sometimes a side effect of Plaquenil. Plaquenil and low white blood count Plaquenil - Effects on Blood Tests especially platelet count, The effect of hydroxychloroquine on glucose control and insulin. Hydroxychloroquine vs hydroxychlorChloroquine lysosome fusionPlaquenil neuropathy A complete blood count CBC is the most commonly performed lab test in the U. S. and is used to analyze red blood cells RBCs, white blood cells WBCs, and platelets. Many people with systemic lupus have abnormal CBCs. White blood cell counts can be low leukopenia due to lupus, immunosuppressive therapy, or the presence of a virus. Complete Blood Count CBC Johns Hopkins Lupus Center. Long-Term Side Effects of Plaquenil for Rheumatoid.. Does Plaquenil tablet reduce the count of white blood cells? - Doctor's.. White blood cell count decreased is found among people who take Plaquenil, especially for people who are female, 60+ old, have been taking the drug for 1 month, also take medication Enbrel, and have High blood pressure. Nov 30, 2018 A low white blood cell count leukopenia is a decrease in disease-fighting cells leukocytes in your blood. Leukopenia is almost always related to a decrease in a certain type of white blood cell neutrophil. The definition of low white blood cell count varies from one medical practice to another. Aug 02, 2010 My Absolute Neutrophils good indicator of immune system function didn't get suppressed to a NORMAL range until I increased the Plaquenil to 600mg/day while still taking the Prednisone. In addition, my white blood cell count was still within a normal range. Expand.