I have been on the plaquenil 200 mgm for about 4 months now. I did stop it for 2 weeks early in the treatment due to having to take a coupld other drugs that seemed to give me side effects. Plaquenil induced rash Plaquenil used for lyme disease Hydroxychloroquine 200 mg for rheumatoid arthritis Hydroxychloroquine how to take Saturday was a week since I stopped taking Plaquenil, aka Hydroxychloroquine, per my doctor's instructions, and I think I am going through some form of withdrawal. I took the drug as a treatment for sarcoidosis and one of the side effects is a reduction in white blood cells, which is what has happened to me. With the Plaquenil I don't think you will find much relief in such a short time on it & at half of a workable dose. I have read about people stopping P & flaring up. Those who stopped it abruptly had real problems similar to what you are experiencing. If you really need to get off it, I would taper down slowly, very slowly. Side Effects. Drug information provided by IBM Micromedex Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. I have done a lot of research on this drug and haven't run into anybody who has complained of the withdrawal effect. I just quit the plaquenil to give my liver a rest at that time. Plaquenil isn a antiparasitic drug with anti-inflammatory affect. Tapering off hydroxychloroquine Will you have Withdrawal syndrome with Plaquenil - eHealthMe, Hydroxychloroquine plaquenil withdrawl? - LUPUS UK Can plaquenil cause tinnitusChloroquine dosage 4-3-3 Hello all, I am currently new to this site and ran across the discussion about stopping Plaquenil. I have been taking Plaquenil for about 8-9 months and thought that it was not helping me because I still have a fair amount of joint pain, fatigue, muscle pain and so many other issues. Stopping plaquenil. DailyStrength. Hydroxychloroquine Oral Route Side Effects - Mayo Clinic. Coming off Hydroxychloroquine I went to see my rheumy. - NRAS. Weaning failure is reported only by a few people who take Plaquenil. We study 48,911 people who have side effects while taking Plaquenil from Food and Drug Administration FDA. Among them, 1 has Weaning failure. Find out below who they are, when they have Weaning failure and more. eHealthMe has been monitoring drugs since 2008. For patients taking hydroxychloroquine to prevent malaria Your doctor may want you to start taking this medicine 1 to 2 weeks before you travel to an area where there is a chance of getting malaria. This will help you to see how you react to the medicine. Nov 14, 2006 I have been taking Plaquenil 400 mg per day for about 2 years now due to lupus flare. When i first started it, I was also started on prednisone to get my inflammation under control. Actually I started on 200 mg per day and about 2 months before tapering off pred, he upped me to 400 mg per day of plaquenil to give it plenty of time to kick in.