Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Plaquenil changed your hair Plaquenil myasthenia gravis View detailed reports from patients taking Hydroxychloroquine Sulfate who experienced decreased appetite. Reports are from official medical reports as well as online extractions from user reviews and forum discussions. Plaquenil is a prescription medication used to reduce pain and swelling caused by diseases of the immune system such as rheumatoid arthritis, juvenile arthritis, and systemic lupus erythematosus SLE. This medication belongs to a group of drugs called DMARDs disease modifying antirheumatic drugs which work by suppressing the excessive activity of the immune system. Plaquenil is an antimalarial medication and Azulfidine EN-tabs is an anti-inflammatory agent and immunomodulatory agent. Side effects of Plaquenil and Azulfidine that are similar include nausea, vomiting, loss of appetite, diarrhea, dizziness, spinning sensation, headache, ringing in your ears, or itching or skin rash. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Plaquenil loss of appetite Abnormal Weight Gain and Gut Microbiota Modifications Are., Plaquenil - Side Effects, Uses, Dosage, Overdose. Fies the itching frim plaquenil stop Side effects of Plaquenil that are different from Aralen include loss of appetite, weight loss, dizziness, spinning sensation, ringing in your ears, mood changes, nervousness, irritability, skin rash, or itching. Side effects of Aralen that are different from Plaquenil include blurred vision, changes in hair color, or muscle weakness. Plaquenil vs. Aralen Prescription Treatment for Malaria.. Plaquenil vs. Azulfidine Prescription Treatment for.. Hydroxychloroquine MedlinePlus Drug Information. Yes, Plaquenil causes both weight loss and loss of appetite. Hence, if the loss of appetite and weight loss started after you started on this drug, then yes, it could be due to Plaquenil. However, if you had loss of appetite and weight loss before your started this drug, then the drug can aggravate the process. Hi there, I did have a loss of appetite on plaquenil, but not in a good way. It was nausea, dizzy spells and anxiety. I am one of the few that had a hard time tolerating it, so I no longer take it. Consumer Medicine Information CMI about Plaquenil hydroxychloroquine sulfate intended for persons living in Australia.