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In another analysis by Cipriani, citalopram was found to be more efficacious than paroxetine and reboxetine, and more acceptable than tricyclics, reboxetine, and venlafaxine, but less efficacious than escitalopram. A meta-analysis, including studies with fluoxetine, paroxetine, sertraline, escitalopram, and citalopram versus placebo, showed SSRIs to be effective in reducing symptoms of premenstrual syndrome, whether taken continuously or just in the luteal phase. A 2009 multisite randomized controlled study found no benefit and some adverse effects in autistic children from citalopram, raising doubts whether SSRIs are effective for treating repetitive behavior in children with autism. This side effect, if present, should subside as the body adjusts to the medication. Citalopram is considered safe and well tolerated in the therapeutic dose range. Distinct from some other agents in its class, it exhibits linear pharmacokinetics and minimal drug interaction potential, making it a better choice for the elderly or comorbid patients. Citalopram is an antidepressant medication used in numerous psychiatric disorders. Citalopram belongs to the Selective Serotonin Reuptake Inhibitor (SSRI) class of drugs, and in most respects works similarly to other SSRIs. It does have a couple key advantages, however; one of which is its effectiveness if treating depression and anxiety---the two conditions for which the majority of patients buy Citalopram to treat. Citalopram is often effective in treating depression and anxiety when other SSRIs failed to produce beneficial results. The other advantage is that Citalopram is, as a general rule, less likely to interact with other medications, making it more suitable for patients also treating other medical conditions. 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